Artemisinin

$70

Artemisinin is an active constituent of the plant Artemisia annua, also known as sweet wormwood or Qinghaosu. Artemisinin is a sesquiterpene endoperoxide lactone, and the biological mechanism of action may be attributable to the generation of carbon-centered free radicals via heme-mediated or mitochondrial activated degradation of endoperoxidase bridges. Sesquiterpene lactones are secondary metabolites of plants that play an important role as attractants, deterrents, and antifeedants simultaneously.

They are bitter compounds, and as such may impact digestion in a manner similar to digestive bitters. They are bitter compounds, and as such may impact digestion in a manner similar to digestive bitters. Artemisinin and its derivatives have been widely studied for their effects against Plasmodium falciparum, the protozoan parasite which causes malaria. Artemisinin-based combination therapies are recommended by the World Health Organization as first-line treatment for uncomplicated malaria in endemic regions. Artemisinin may impact the flora of the digestive system, genitourinary tract, and beyond, having activity against microbes including Helicobacter pylori, Escherichia coli UPEC, Staphylococcus aureus, and Pseudomonas aeruginosa. It also may impact biofilms which make infections such as Candida albicans resistant to treatment.

Because of the low bioavailability of traditional oral formulations of artemisinin, the use of derivatives such as artesunate (water-soluble) and artemether (oil-soluble) or alternate dosing strategies such as liposomes have been investigated. First-pass metabolism of artemisinin and these derivatives limit oral bioavailability to 30%. Liposomal delivery systems have been shown to lead to more stable artemisinin plasma concentrations, suggesting that they lead to an extended release and thereby prolonged systemic effect. Additionally, more immediate effects have also been seen with liposomal formulations than conventional.

INGREDIENTS

Serving Size 5 ml (1 tsp)

Servings Per Container 24

Contains

Amount Per Serving

Artemisinin
40 mg
Phosphatidylcholine (from purified soy bean lecithin)
450 mg

Other Ingredients: Glycerin, Ethanol, Water, Medium-Chain Tricglycerides

Suggested Use: Use 1 tsp (5ml) 1 to 3 times per day as directed by your health practitioner. Best used in a cycle of 10 days on, and 4 days off. It is advisable to monitor liver function enzymes (LFT's) during usage. May be taken directly by mouth or mixed into water or juice (grapefruit juice is best). Store refrigerated and use within 60 days of opening.

 

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